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Ojo, Babatunde

Department: 
College of Arts and Sciences Department
Location: 
Academic Classroom & Lab Building, Rm. 207
Phone: 
(478) 825-6843
Email: 
ojob@fvsu.edu
Fax: 
(478) 825-6116

Director and Chief Academic Officer – FAKS Allied Education Training Center, Atlanta, GA. Directed the academic affairs of the institution, including recruitment, training and other daily administration and management of both staff and faculty of the institution.
Research Officer (Chemical development); National Research for Chemical Technology; Federal Ministry of Science and Technology, Nigeria. Conducted independent research and supervised junior chemists in projects aimed at the development of industrial chemicals.
Standards Officer (Chemicals): Standards Organization of Nigeria, Federal Ministry of Industries; Lagos, Nigeria. Writing and enforcement of various industrial standards for foreign and indigenous chemical and food products. Provided mentoring to junior chemists in the writing and enforcement of industrial standards. Conducted industrial inspections for quality control enforcement for food and chemical products.
TEACHING AND RESEARCH (Representative)

08/2008 –To Date: Assistant Professor of Chemistry – Department of Chemistry, College of Arts and Sciences, Fort Valley State University, Fort Valley, Georgia. Faculty teaching and advisement of undergraduate science and non-science majors in the areas of organic chemistry, principles of chemistry, and biochemistry.

08/2007 – 09/2008: Assistant Professor of Chemistry and MESA Director: Division of Natural Sciences, Atlanta Metropolitan College, Atlanta, Georgia. Faculty teaching and advising of undergraduate chemistry and non-chemistry majors in the areas of organic chemistry, general chemistry, and survey of chemistry. Performed administrative and management duties in addition to my faculty assignments as the Director of the MESA (Mathematics Engineering Science Achievement) Center at the College.

08/2006 – To Date: Assistant Professor of Chemistry and Biochemistry (Adjunct), Department of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, GA. Faculty teaching and laboratory instruction of undergraduate chemistry majors and non-majors in the areas of organic chemistry, principles of chemistry, and biochemistry

Faculty Bio
Education: 

Ph.D. (Medicinal chemistry): March 25, 1995.
Department of Medicinal and Biological Chemistry, University of Toledo, Toledo, OH.

M.S. (Medicinal chemistry): June 13, 1992.
Department of Medicinal and Biological Chemistry, University of Toledo, Toledo, OH.

M.S. (Pharmaceutical Chemistry): June 1986.
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello Univ. Zaria, Nigeria

B.Sc. (Chemistry): June 1, 1981.
Department of Chemistry, University of Lagos, Lagos, Nigeria

Publications: 

Babatunde Ojo. Efficient synthesis of a new series of piperidine ring modified Thiopene, furan and pyridyl alcohol and methyl ether analogues of (±)-threo-methyl phenyl (piperidine-2-yl) acetate. OCAIJ, 8 (1), 5-14, 2012.

Babatunde Ojo and Bejoy K. Chowdhury. Synthesis of {2, 3-dihydro- 7-halopyrrolo-[(2, 1-b)]-quinazolin-9-(1H)-one and 2, 3-dihydro-5, 7-dihalopyrrolo-[(2, 1-b)]-quinazolin-9-(1H)-one}: New Analogs of Deoxyvasicinone. Synthetic
Communications, 42 (7), 1002-1009, 2012.

Babatunde Ojo. Efficient synthesis of a new series of piperidine ring modified analogues of (±)-threo-methyl phenyl (piperidine-2-yl) acetate. Synthetic Communications, 42 (12), 1731-1745, 2012.

Babatunde Ojo. Efficient synthesis of a new series of piperidine ring modified alcohol and methyl ether analogues of (±)-threo-methyl phenyl (piperidine-2-yl) acetate. Synthetic Communications, 42 (19), 2818-2830, 2012.

Jermaine Butler, Babatunde Ojo and Adegboye Adeyemo. Ligand exchange reactions involving vitamin B1 complex and various porphyrin species. Georgia Journal of Science, 2000, 58 (No. 1), 56.

Howard M. Deutsch, Margaret M. Schweri, Stephen Holtzman, Xiaocong Ye and Babatunde Ojo. Structure-activity relationships for methylphenidate analogs and comparison to Cocaine and Tropanes. NIDA Research Monograph, RM 179, 182, 1999.

Howard M. Deutsch, Babatunde Ojo, Xiaocong Ye, Margaret M. Schweri, and Stephen Holtzman. Cocaine treatment agents: synthesis and pharmacology of N-substituted methylphenidate analogs. NIDA Research Monograph, RM 178, 76, 1998.

Messer, W.S. Jr., Abuh, Y.F., Yang L., Periyasamy, S., Ngur, D.O., Edgar, M.A.N., El-Assadi, A.A., Dunbar, P.G, Rocknich, S., Rho, T., Fang, Z., Ojo, B., Zhang, H., Nagy, P.I., and Huzl, J.J. III. Synthesis and Biological Characterization of 1, 4, 5, 6-tetrahydropyrimidine and 2-Amino-3, 4, 5, 6-tetrahydropyridine derivatives as selective m1 agonists. J. Med. Chem., 1997, 40, 1230-1246.

Ojo, B., Dunbar, P.G., Durant, G.J.; Huzl, J.J. III, Periyasamy, S., Ngur, D.O., El-Assadi, A.A., Hoss, W.P., and Messer, W.S. Jr.; Synthesis and biochemical activity of novel amidine derivatives as m1 muscarinic receptor agonists. Bioorgan. And Med. Chem., 1996, 4 (Issue 10), 1605-1615.

Ojo, B., Findsen, L.A., Igarashi, N., Kong, B. and Chowdhury, B.K.; Synthesis and bronchodilator activity of four new derivatives of deoxyvasicine. Drug Design and Discovery, 1996, 14, 1-14.

Ojo, B., Dunbar, P.G., Durant, G.J., Huzl, J.J. III, El-Assadi, A.A., Periyasamy, S., Ngur, D.O., Hoss, W.P. and Messer, W.S., Jr.; Synthesis and structure-activity relationships of novel amidine derivatives as muscarinic receptor subtype-selective agonists. Life Sci., 1995, 56 (No. 11), 1005.
Abuh, Y.F., Dunbar, P.G., Durant, G.J., Ojo, B., Periyasamy, S., Hoss, W.P., and Messer,

W.S., Jr.; Synthesis of 2-amino-alkoxycarbonyl-3, 4, 5, 6-tetrahydropyridines and 2-amino-1, 4, 5, 6-tetrahydropyrmidines for muscarinic receptor subtypes. Life Sci., 1995, 56 (No. 11), 1007.

Messer, W.S., Jr., Abuh, Y.F., El-Assadi, A.A., Liu, Y., Ojo, B. and Ryan, K.; Neurochemical evaluation of the selective m1 muscarinic receptor agonist CDD-0097-A. Life Sci., 1995, 56 (No. 11), 1006.

Messer, W.S., Jr., M.A.N. Edgar, B. Ojo, H. Zhang, J.J. Huzl, III and A.A. El-Assadi. Molecular studies of agonist interactions with m1 receptors. Society for Neuroscience, 21: 2039, 1995.

Ojo, B. and Chowdhury, B.K.; Synthesis of 1, 2, 3, and 9-tetrahydro-7-bromo-6-hydroxy-5 methoxypryrrolo-[2, 1-b]-quinazoline: A new analog of deoxyvasicine. Synthetic Communications, 1995, 25, 4, 569-572.

Messer, W.S., Jr., Ojo, B., Zhang, H., Huzl, J.J. III, El-Assadi, A.A., Sbeih, S., and Edgar, M.A.N.; Development of novel 1,4,5,6-tetrahydropyrimidine derivatives as selective muscarinic agonists, in Perspective in Receptor Research (P. Angeli, U. Gulin and W. Quaglia, eds.) 10th Camerino-Noordwijkerhout Symposium, Universita’Degli Studi di Camerino, Aula Magna, Camerino, Italy, pp. 87-88 (1995).

Dunbar, P.G., Durant, G.J., Rho, T., Ojo, B., El-Assadi, A.A., Ngur, D.O., Periyasamy, S., Hoss, W.P. and Messer, W.S., Jr.; Design, synthesis, and neurochemical evaluation of 2-amino-5-alkoxycarbonyl-3,4,5,6-tetrahydropyridines and 2-amino-5-alkoxycarbonyl-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists. J. Med. Chem., 1994, 37, 17, 2774-2782.

Research Interests: 

Heterocyclic Chemistry Drug Development Research: Design, synthesis and development of cyclic amidine derivatives (heterocyclic compounds) as selective m1 muscarinic receptor agonists for the treatment of the cognitive deficits and memory impairments found in Alzheimer’s disease.

Natural Product Drug Development Research: Collaborative research with the National Institute for Pharmaceutical Research and Development (Abuja, Nigeria) for the development of quinazoline derivatives as novel bronchodilator and anticonvulsant agents based on natural products, and other agents that may be of possible clinical utility in such condition as premenstrual tension, dysmenorrhea or threatened abortion.

Anticancer Drug Development Research: Design, synthesis and development of novel and selective Topoisomerase II inhibitors for treatment of cancer.

CNS Drug Development Research: Design and synthesis of selective, efficacious and centrally active serotonergic/nicotinic agents for the treatment of CNS disorders such as migraine and psychosis. Design, synthesis and development of novel and selective treatment agents for neurological disorders.

Quantum and Computational Medicinal Chemistry. Theoretical model chemistries by means of ab initio and semi-empirical molecular orbital calculations to study structures and properties of novel compounds of importance in biology and medicine.

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